6CYN

CTX-M-14 N106S/D240G mutant

Summary for 6CYN

• Entry DOI: 10.2210/pdb6cyn/pdb
• Related: 6CYK
• Descriptor: Beta-lactamase (2 entities in total)
• Functional Keywords: beta-lactamase ctx-m-14, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 8
• Total formula weight: 223323.86

Authors

Patel, M.P.,Hu, L.,Sankaran, B.,Brown, C.,Prasad, B.V.V.,Palzkill, T. (deposition date: 2018-04-06, release date: 2018-10-10, Last modification date: 2023-10-04)

• Primary citation: Patel, M.P.,Hu, L.,Brown, C.A.,Sun, Z.,Adamski, C.J.,Stojanoski, V.,Sankaran, B.,Prasad, B.V.V.,Palzkill, T.; Synergistic effects of functionally distinct substitutions in beta-lactamase variants shed light on the evolution of bacterial drug resistance.; J. Biol. Chem., 293:17971-17984, 2018; PubMed: 30275013; DOI: 10.1074/jbc.RA118.003792

Experimental method

X-RAY DIFFRACTION (1.6 Å)