6CYK
CTX-M-14 N106S mutant
Summary for 6CYK
Entry DOI | 10.2210/pdb6cyk/pdb |
Descriptor | Beta-lactamase, ACETATE ION (3 entities in total) |
Functional Keywords | beta-lactamase ctx-m-14, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 56065.13 |
Authors | Patel, M.P.,Hu, L.,Sankaran, B.,Brown, C.,Prasad, B.V.V.,Palzkill, T. (deposition date: 2018-04-06, release date: 2018-10-10, Last modification date: 2023-10-04) |
Primary citation | Patel, M.P.,Hu, L.,Brown, C.A.,Sun, Z.,Adamski, C.J.,Stojanoski, V.,Sankaran, B.,Prasad, B.V.V.,Palzkill, T. Synergistic effects of functionally distinct substitutions in beta-lactamase variants shed light on the evolution of bacterial drug resistance. J. Biol. Chem., 293:17971-17984, 2018 Cited by PubMed: 30275013DOI: 10.1074/jbc.RA118.003792 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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