6CRK
Heterotrimeric G-protein in complex with an antibody fragment
Summary for 6CRK
Entry DOI | 10.2210/pdb6crk/pdb |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | heterotrimeric g-protein antibody fragment, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 114428.43 |
Authors | Maeda, S.,Dawson, R.,Kobilka, B. (deposition date: 2018-03-19, release date: 2018-10-24, Last modification date: 2023-10-04) |
Primary citation | Maeda, S.,Koehl, A.,Matile, H.,Hu, H.,Hilger, D.,Schertler, G.F.X.,Manglik, A.,Skiniotis, G.,Dawson, R.J.P.,Kobilka, B.K. Development of an antibody fragment that stabilizes GPCR/G-protein complexes. Nat Commun, 9:3712-3712, 2018 Cited by PubMed: 30213947DOI: 10.1038/s41467-018-06002-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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