6CRK

Heterotrimeric G-protein in complex with an antibody fragment

6CRK の概要

• エントリーDOI: 10.2210/pdb6crk/pdb
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• 機能のキーワード: heterotrimeric g-protein antibody fragment, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 114428.43

構造登録者

Maeda, S.,Dawson, R.,Kobilka, B. (登録日: 2018-03-19, 公開日: 2018-10-24, 最終更新日: 2023-10-04)

• 主引用文献: Maeda, S.,Koehl, A.,Matile, H.,Hu, H.,Hilger, D.,Schertler, G.F.X.,Manglik, A.,Skiniotis, G.,Dawson, R.J.P.,Kobilka, B.K.; Development of an antibody fragment that stabilizes GPCR/G-protein complexes.; Nat Commun, 9:3712-3712, 2018; PubMed: 30213947; DOI: 10.1038/s41467-018-06002-w

実験手法

X-RAY DIFFRACTION (2 Å)