6CLU
Staphylococcus aureus Dihydropteroate Synthase (saDHPS) F17L E208K double mutant structure
Summary for 6CLU
Entry DOI | 10.2210/pdb6clu/pdb |
Descriptor | Dihydropteroate synthase (2 entities in total) |
Functional Keywords | antibiotic resistance mutations, sulfonamide resistance, antimicrobial protein |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 4 |
Total formula weight | 129627.74 |
Authors | Gajewski, S.,Griffith, E.C.,Wu, Y.,White, S.W. (deposition date: 2018-03-02, release date: 2018-08-22, Last modification date: 2024-03-13) |
Primary citation | Griffith, E.C.,Wallace, M.J.,Wu, Y.,Kumar, G.,Gajewski, S.,Jackson, P.,Phelps, G.A.,Zheng, Z.,Rock, C.O.,Lee, R.E.,White, S.W. The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations inStaphylococcus aureusDihydropteroate Synthase. Front Microbiol, 9:1369-1369, 2018 Cited by PubMed: 30065703DOI: 10.3389/fmicb.2018.01369 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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