6CLU

Staphylococcus aureus Dihydropteroate Synthase (saDHPS) F17L E208K double mutant structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Dihydropteroate synthase	polymer	291	32406.9	4	UniProt (O05701) Pfam (PF00809)	Staphylococcus aureus	DHPS,Dihydropteroate pyrophosphorylase
2	E, F, G, H (A, B, C, D)	water	water		18.0	197	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 267 (UniProt: O05701)

PDB	External Database	Details
Met -23	-	initiating methionine
Gly -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
His -8	-	expression tag
Ile -7	-	expression tag
Glu -6	-	expression tag
Gly -5	-	expression tag
Arg -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Leu -1	-	expression tag
Glu 0	-	expression tag
Leu 17	Phe 17	engineered mutation
Lys 208	Glu 208	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	129627.7
All*	Total formula weight	129627.7

*Water molecules are not included.