6CHT
HNF4alpha in complex with the corepressor EBP1 fragment
Summary for 6CHT
Entry DOI | 10.2210/pdb6cht/pdb |
Descriptor | Hepatocyte nuclear factor 4-alpha, Proliferation-associated protein 2G4, LAURIC ACID, ... (4 entities in total) |
Functional Keywords | hnf4alpha, ebp1, nuclear receptor, co-repressor, protein-protein interaction, gene regulation, insulin secretion, diabetes, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 20 |
Total formula weight | 450999.28 |
Authors | |
Primary citation | Han, E.H.,Singh, P.,Lee, I.K.,Urrutia, R.,Chi, Y.I. ErbB3-binding protein 1 (EBP1) represses HNF4 alpha-mediated transcription and insulin secretion in pancreatic beta-cells. J.Biol.Chem., 294:13983-13994, 2019 Cited by PubMed: 31362984DOI: 10.1074/jbc.RA119.009558 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.174 Å) |
Structure validation
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