6CGO

Molecular basis for condensation domain-mediated chain release from the enacyloxin polyketide synthase

Summary for 6CGO

• Entry DOI: 10.2210/pdb6cgo/pdb
• Descriptor: Condensation domain protein, PHOSPHATE ION (3 entities in total)
• Functional Keywords: polyketide, nonribosomal peptide synthetase, biosynthetic protein
• Biological source: Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD))
• Total number of polymer chains: 2
• Total formula weight: 119713.23

Authors

Valentic, T.R.,Tsai, S.C.,Challis, G.L.,Lewandowski, J.R.,Kosol, S.,Gallo, A.,Griffiths, D.,Masschelein, J.L.,Jenner, M.,De los Santos, E. (deposition date: 2018-02-20, release date: 2019-02-27, Last modification date: 2024-03-13)

• Primary citation: Kosol, S.,Gallo, A.,Griffiths, D.,Valentic, T.R.,Masschelein, J.,Jenner, M.,de Los Santos, E.L.C.,Manzi, L.,Sydor, P.K.,Rea, D.,Zhou, S.,Fulop, V.,Oldham, N.J.,Tsai, S.C.,Challis, G.L.,Lewandowski, J.R.; Structural basis for chain release from the enacyloxin polyketide synthase.; Nat.Chem., 11:913-923, 2019; PubMed: 31548674; DOI: 10.1038/s41557-019-0335-5

Experimental method

X-RAY DIFFRACTION (2 Å)