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6CEB

Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry

Summary for 6CEB
Entry DOI10.2210/pdb6ceb/pdb
EMDB information7461 7462 7463
DescriptorInsulin receptor, Insulin A chain, Insulin B chain, ... (9 entities in total)
Functional Keywordssignaling, signaling protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains8
Total formula weight234314.85
Authors
Scapin, G.,Dandey, V.P.,Zhang, Z.,Strickland, C.,Potter, C.S.,Carragher, B. (deposition date: 2018-02-11, release date: 2018-03-14, Last modification date: 2020-07-29)
Primary citationScapin, G.,Dandey, V.P.,Zhang, Z.,Prosise, W.,Hruza, A.,Kelly, T.,Mayhood, T.,Strickland, C.,Potter, C.S.,Carragher, B.
Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Nature, 556:122-125, 2018
Cited by
PubMed: 29512653
DOI: 10.1038/nature26153
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.7 Å)
Structure validation

217705

數據於2024-03-27公開中

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