6CC8
Crystal structure MBD3 MBD domain in complex with methylated CpG DNA
Summary for 6CC8
Entry DOI | 10.2210/pdb6cc8/pdb |
Descriptor | Methyl-CpG-binding domain protein 3, methylated CpG DNA, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | structural genomics consortium, sgc, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 32894.55 |
Authors | Liu, K.,Tempel, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2018-02-06, release date: 2018-04-04, Last modification date: 2023-10-04) |
Primary citation | Liu, K.,Lei, M.,Wu, Z.,Gan, B.,Cheng, H.,Li, Y.,Min, J. Structural analyses reveal that MBD3 is a methylated CG binder. Febs J., 286:3240-3254, 2019 Cited by PubMed: 30980593DOI: 10.1111/febs.14850 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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