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6CBV

Crystal structure of BRIL bound to an affinity matured synthetic antibody.

Summary for 6CBV
Entry DOI10.2210/pdb6cbv/pdb
DescriptorHeavy chain, Fab fragment, Light Chain, Fab fragment, BRIL, ... (7 entities in total)
Functional Keywords4-helix bundle, fusion protein, synthetic antibody, fab fragment, fusion protein in complex with fab, immune system
Biological sourceHomo sapiens
More
Total number of polymer chains3
Total formula weight59759.49
Authors
Mukherjee, S.,Skrobek, B.,Kossiakoff, A.A. (deposition date: 2018-02-05, release date: 2019-02-06, Last modification date: 2023-10-04)
Primary citationMukherjee, S.,Erramilli, S.K.,Ammirati, M.,Alvarez, F.J.D.,Fennell, K.F.,Purdy, M.D.,Skrobek, B.M.,Radziwon, K.,Coukos, J.,Kang, Y.,Dutka, P.,Gao, X.,Qiu, X.,Yeager, M.,Eric Xu, H.,Han, S.,Kossiakoff, A.A.
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11:1598-1598, 2020
Cited by
PubMed: 32221310
DOI: 10.1038/s41467-020-15363-0
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.872 Å)
Structure validation

217705

數據於2024-03-27公開中

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