6CAX
Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT805
Summary for 6CAX
Entry DOI | 10.2210/pdb6cax/pdb |
Related | 5UPG |
Descriptor | UDP-3-O-acyl-N-acetylglucosamine deacetylase, (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-{2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}butanamide, ZINC ION, ... (6 entities in total) |
Functional Keywords | ssgcid, lpxc, lipid a biosynthesis, structural genomics, seattle structural genomics center for infectious disease, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 35646.48 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-02-01, release date: 2019-02-13, Last modification date: 2023-10-04) |
Primary citation | Phan, J.N.,Delker, S.L.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E. Crystal structure of LpxC from Pseudomonas aeruginosa in complex with PT805 to be published, |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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