6C9C
Crystal structure of LpxC from Pseudomonas aeruginosa in complex with racemic ligand PT803
Summary for 6C9C
Entry DOI | 10.2210/pdb6c9c/pdb |
Related | 5UPG 5VWM |
Descriptor | UDP-3-O-acyl-N-acetylglucosamine deacetylase, (2R)-4-[4-{4-[(5-chloro-6-methoxypyridin-3-yl)methoxy]phenyl}-2-oxo-3,6-dihydropyridin-1(2H)-yl]-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2S)-4-[4-{4-[(5-chloro-6-methoxypyridin-3-yl)methoxy]phenyl}-2-oxo-3,6-dihydropyridin-1(2H)-yl]-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, ... (6 entities in total) |
Functional Keywords | inhibitor, structural genomics, seattle structural genomics center for infectious disease, ssgcid, lpxc, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Pseudomonas aeruginosa (strain UCBPP-PA14) |
Total number of polymer chains | 1 |
Total formula weight | 35013.90 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-01-26, release date: 2019-03-13, Last modification date: 2023-10-04) |
Primary citation | Delker, S.L.,Mayclin, S.J.,Phan, J.N.,Abendroth, J.,Lorimer, D.,Edwards, T.E. Crystal structure of LpxC from Pseudomonas aeruginosa in complex with ligand PT803 to be published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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