6C8W
Crystal structure of Aspartate Semialdehyde Dehydrogenase with NADP from Blastomyces dermatitidis
Summary for 6C8W
Entry DOI | 10.2210/pdb6c8w/pdb |
Descriptor | Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | rossman fold, antifungal inhibitor complex, nadp cofactor, oxidoreductase |
Biological source | Blastomyces gilchristii (Blastomyces dermatitidis) |
Total number of polymer chains | 2 |
Total formula weight | 81792.76 |
Authors | Dahal, G.P.,Viola, R.E. (deposition date: 2018-01-25, release date: 2019-01-30, Last modification date: 2023-10-04) |
Primary citation | Dahal, G.P.,Viola, R.E. Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase. Biochem.Biophys.Res.Commun., 503:2848-2854, 2018 Cited by PubMed: 30107909DOI: 10.1016/j.bbrc.2018.08.053 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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