6C8W
Crystal structure of Aspartate Semialdehyde Dehydrogenase with NADP from Blastomyces dermatitidis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004073 | molecular_function | aspartate-semialdehyde dehydrogenase activity |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0046983 | molecular_function | protein dimerization activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0004073 | molecular_function | aspartate-semialdehyde dehydrogenase activity |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0046983 | molecular_function | protein dimerization activity |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue NAP A 401 |
| Chain | Residue |
| A | GLY13 |
| A | LEU87 |
| A | ASP88 |
| A | PRO89 |
| A | ALA91 |
| A | ASN109 |
| A | ALA110 |
| A | SER185 |
| A | GLY186 |
| A | GLY188 |
| A | ASN340 |
| A | THR15 |
| A | THR341 |
| A | ALA345 |
| A | HOH525 |
| A | HOH540 |
| A | GLY16 |
| A | ALA17 |
| A | VAL18 |
| A | ALA39 |
| A | SER40 |
| A | SER43 |
| A | GLY86 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue NAP B 401 |
| Chain | Residue |
| B | GLY13 |
| B | THR15 |
| B | GLY16 |
| B | ALA17 |
| B | VAL18 |
| B | ALA39 |
| B | SER40 |
| B | SER43 |
| B | GLY86 |
| B | LEU87 |
| B | ASP88 |
| B | PRO89 |
| B | ALA91 |
| B | ASN109 |
| B | ALA110 |
| B | ASN153 |
| B | CYS154 |
| B | GLY188 |
| B | GLU208 |
| B | LYS211 |
Functional Information from PROSITE/UniProt
| site_id | PS01103 |
| Number of Residues | 15 |
| Details | ASD Aspartate-semialdehyde dehydrogenase signature. VSvaCnRVpvldGHT |
| Chain | Residue | Details |
| A | VAL238-THR252 |
