6C8W
Crystal structure of Aspartate Semialdehyde Dehydrogenase with NADP from Blastomyces dermatitidis
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004073 | molecular_function | aspartate-semialdehyde dehydrogenase activity |
A | 0006520 | biological_process | amino acid metabolic process |
A | 0008652 | biological_process | amino acid biosynthetic process |
A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
A | 0046983 | molecular_function | protein dimerization activity |
A | 0050661 | molecular_function | NADP binding |
A | 0051287 | molecular_function | NAD binding |
B | 0004073 | molecular_function | aspartate-semialdehyde dehydrogenase activity |
B | 0006520 | biological_process | amino acid metabolic process |
B | 0008652 | biological_process | amino acid biosynthetic process |
B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
B | 0046983 | molecular_function | protein dimerization activity |
B | 0050661 | molecular_function | NADP binding |
B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 23 |
Details | binding site for residue NAP A 401 |
Chain | Residue |
A | GLY13 |
A | LEU87 |
A | ASP88 |
A | PRO89 |
A | ALA91 |
A | ASN109 |
A | ALA110 |
A | SER185 |
A | GLY186 |
A | GLY188 |
A | ASN340 |
A | THR15 |
A | THR341 |
A | ALA345 |
A | HOH525 |
A | HOH540 |
A | GLY16 |
A | ALA17 |
A | VAL18 |
A | ALA39 |
A | SER40 |
A | SER43 |
A | GLY86 |
site_id | AC2 |
Number of Residues | 20 |
Details | binding site for residue NAP B 401 |
Chain | Residue |
B | GLY13 |
B | THR15 |
B | GLY16 |
B | ALA17 |
B | VAL18 |
B | ALA39 |
B | SER40 |
B | SER43 |
B | GLY86 |
B | LEU87 |
B | ASP88 |
B | PRO89 |
B | ALA91 |
B | ASN109 |
B | ALA110 |
B | ASN153 |
B | CYS154 |
B | GLY188 |
B | GLU208 |
B | LYS211 |
Functional Information from PROSITE/UniProt
site_id | PS01103 |
Number of Residues | 15 |
Details | ASD Aspartate-semialdehyde dehydrogenase signature. VSvaCnRVpvldGHT |
Chain | Residue | Details |
A | VAL238-THR252 |