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6C6N

Human squalene epoxidase (SQLE, squalene monooxygenase) structure with FAD and Cmpd-4"

Summary for 6C6N
Entry DOI10.2210/pdb6c6n/pdb
Related6C6P 6C6R
DescriptorSqualene monooxygenase, GLYCEROL, SULFATE ION, ... (7 entities in total)
Functional Keywordscholesterol synthesis pathway, sqle, erg1, fad-dependent monooxygenase, squalene hydroxylase, squalene-2, 3-epoxidase, flavoprotein, oxidoreductase-oxidoreductase inhibitor complex, flavoprotein-inhibitor complex, flavoprotein/inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight109122.65
Authors
Padyana, A.K.,Jin, L. (deposition date: 2018-01-19, release date: 2019-01-16, Last modification date: 2024-03-13)
Primary citationPadyana, A.K.,Gross, S.,Jin, L.,Cianchetta, G.,Narayanaswamy, R.,Wang, F.,Wang, R.,Fang, C.,Lv, X.,Biller, S.A.,Dang, L.,Mahoney, C.E.,Nagaraja, N.,Pirman, D.,Sui, Z.,Popovici-Muller, J.,Smolen, G.A.
Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase.
Nat Commun, 10:97-97, 2019
Cited by
PubMed: 30626872
DOI: 10.1038/s41467-018-07928-x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

217705

건을2024-03-27부터공개중

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