6C55
Crystal structure of Staphylococcus aureus Ketol-acid Reductosimerrase with hydroxyoxamate inhibitor 3
Summary for 6C55
Entry DOI | 10.2210/pdb6c55/pdb |
Descriptor | Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total) |
Functional Keywords | ketol-acid reductoisomerase, inhibitor, oxidoreductase |
Biological source | Staphylococcus aureus (strain bovine RF122 / ET3-1) |
Total number of polymer chains | 2 |
Total formula weight | 77886.90 |
Authors | Kandale, A.,Patel, K.M.,Zheng, S.,You, L.,Guddat, L.W.,Schenk, G.,Schmbri, M.,McGeary, R.P. (deposition date: 2018-01-14, release date: 2019-01-16, Last modification date: 2023-10-04) |
Primary citation | Kandale, A.,Patel, K.M.,Zheng, S.,You, L.,Guddat, L.W.,Schenk, G.,Schmbri, M.,McGeary, R.P. Design, synthesis, in vitro activity and crystallisation of novel N-isopropyl-N-hydroxyoxamate derivatives as ketol-acid reductoisomerase (KARI) inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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