6C55
Crystal structure of Staphylococcus aureus Ketol-acid Reductosimerrase with hydroxyoxamate inhibitor 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ketol-acid reductoisomerase (NADP(+)) | polymer | 340 | 37886.6 | 2 | UniProt (Q2YUF3) Pfam (PF07991) Pfam (PF01450) | Staphylococcus aureus (strain bovine RF122 / ET3-1) | KARI,Acetohydroxy-acid isomeroreductase,AHIR,Alpha-keto-beta-hydroxylacyl reductoisomerase,Ketol-acid reductoisomerase type 1,Ketol-acid reductoisomerase type I |
| 2 | C, D, G, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | E, K (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 4 | F, H (A) | (cyclohexylamino)(oxo)acetic acid | non-polymer | 171.2 | 2 | Chemie (EKD) | |||
| 5 | I (A) | [cyclohexyl(hydroxy)amino](oxo)acetic acid | non-polymer | 187.2 | 1 | Chemie (EKA) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 334 (UniProt: Q2YUF3)
| PDB | External Database | Details |
|---|---|---|
| His 335 | - | expression tag |
| His 336 | - | expression tag |
| His 337 | - | expression tag |
| His 338 | - | expression tag |
| His 339 | - | expression tag |
| His 340 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75773.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2113.6 | |
| All* | Total formula weight | 77886.9 |
