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6C4X

Cross-alpha Amyloid-like Structure alphaAmmem

Summary for 6C4X
Entry DOI10.2210/pdb6c4x/pdb
Descriptorcross-alpha amyloid-like membrane peptide alpha-AmMEM, (4S)-2-METHYL-2,4-PENTANEDIOL, ZINC ION, ... (4 entities in total)
Functional Keywordsprotein design, cross-alpha amyloid, de novo protein
Biological sourcesynthetic construct
Total number of polymer chains8
Total formula weight22780.55
Authors
Liu, L.,Zhang, S.Q. (deposition date: 2018-01-13, release date: 2018-08-15, Last modification date: 2024-03-13)
Primary citationZhang, S.Q.,Huang, H.,Yang, J.,Kratochvil, H.T.,Lolicato, M.,Liu, Y.,Shu, X.,Liu, L.,DeGrado, W.F.
Designed peptides that assemble into cross-alpha amyloid-like structures.
Nat. Chem. Biol., 14:870-875, 2018
Cited by
PubMed: 30061717
DOI: 10.1038/s41589-018-0105-5
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.55 Å)
Structure validation

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