6C4K
Full length hUGDH with A104L substitution in the absence of ligand
Summary for 6C4K
Entry DOI | 10.2210/pdb6c4k/pdb |
Descriptor | UDP-glucose 6-dehydrogenase, PHOSPHATE ION, SODIUM ION, ... (4 entities in total) |
Functional Keywords | hugdh, human udp-glucose dehydrogenase, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 165715.96 |
Authors | Beattie, N.R.,Pioso, B.J.,Wood, Z.A. (deposition date: 2018-01-12, release date: 2018-05-16, Last modification date: 2023-10-04) |
Primary citation | Beattie, N.R.,Pioso, B.J.,Sidlo, A.M.,Keul, N.D.,Wood, Z.A. Hysteresis and Allostery in Human UDP-Glucose Dehydrogenase Require a Flexible Protein Core. Biochemistry, 57:6848-6859, 2018 Cited by PubMed: 30457329DOI: 10.1021/acs.biochem.8b00497 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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