6C0E

Crystal Structure of Isocitrate Dehydrogenase from Legionella pneumophila with bound NADPH with an alpha-ketoglutarate adduct

Summary for 6C0E

• Entry DOI: 10.2210/pdb6c0e/pdb
• Descriptor: Isocitrate dehydrogenase, (3~{S})-3-[(4~{S})-3-aminocarbonyl-1-[(2~{R},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4~{H}-pyridin-4-yl]-2-oxidanylidene-pentanedioic acid, GLYCINE, ... (5 entities in total)
• Functional Keywords: ssgcid, isocitrate dehydrogenase, 2-oxoglutarate, ketoglutarate, nadph, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase
• Biological source: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
• Total number of polymer chains: 2
• Total formula weight: 94287.41

Authors

Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2017-12-29, release date: 2018-02-07, Last modification date: 2023-10-04)

• Primary citation: Dranow, D.M.,Mayclin, S.J.,Lorimer, D.D.,Edwards, T.E.; Crystal Structure of Isocitrate Dehydrogenase from Legionella pneumophila with bound NADPH with an ??-ketoglutarate adduct; to be published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)