6BVS

Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142A from Cupriavidus metallidurans in complex with 4-Cl-3-HAA

Summary for 6BVS

Entry DOI	10.2210/pdb6bvs/pdb
Descriptor	3-hydroxyanthranilate 3,4-dioxygenase, 4-CHLORO-3-HYDROXYANTHRANILIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywords	complex structure, dioxygenase, mutant i142a, oxidoreductase
Biological source	Cupriavidus metallidurans (Ralstonia metallidurans)
Total number of polymer chains	1
Total formula weight	22969.71
Authors	Yang, Y.,Liu, F.,Liu, A. (deposition date: 2017-12-13, release date: 2018-06-06, Last modification date: 2023-10-04)
Primary citation	Yang, Y.,Liu, F.,Liu, A. Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities. J. Biol. Chem., 293:10415-10424, 2018 Cited by PubMed: 29784877 DOI: 10.1074/jbc.RA118.002698 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.318 Å)

Structure validation