6BVS
Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142A from Cupriavidus metallidurans in complex with 4-Cl-3-HAA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 3-hydroxyanthranilate 3,4-dioxygenase | polymer | 195 | 22548.3 | 1 | UniProt (Q1LCS4) Pfam (PF06052) In PDB | Cupriavidus metallidurans (Ralstonia metallidurans) | 3-hydroxyanthranilate oxygenase,3-HAO,3-hydroxyanthranilic acid dioxygenase,HAD |
2 | A | 4-CHLORO-3-HYDROXYANTHRANILIC ACID | non-polymer | 187.6 | 1 | Chemie (4AA) | |||
3 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
4 | A | FE (II) ION | non-polymer | 55.8 | 2 | Chemie (FE2) | |||
5 | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence modifications
A: 1 - 174 (UniProt: Q1LCS4)
PDB | External Database | Details |
---|---|---|
Met -20 | - | expression tag |
Gly -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Ser -8 | - | expression tag |
Ser -7 | - | expression tag |
Gly -6 | - | expression tag |
His -5 | - | expression tag |
Ile -4 | - | expression tag |
Glu -3 | - | expression tag |
Gly -2 | - | expression tag |
Arg -1 | - | expression tag |
His 0 | - | expression tag |
Ala 142 | Ile 142 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 22548.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 421.4 | |
All* | Total formula weight | 22969.7 |