6BU0
Crystal structure of the PI3KC2alpha C2 domain in complex with IP6
Summary for 6BU0
Entry DOI | 10.2210/pdb6bu0/pdb |
Related | 2B3R 6BTY 6BTZ |
Descriptor | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ... (5 entities in total) |
Functional Keywords | c2 domain, lipid binding, phosphoinositide, pi3-kinase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 47750.93 |
Authors | Chen, K.-E.,Collins, B.M. (deposition date: 2017-12-08, release date: 2018-10-17, Last modification date: 2023-10-04) |
Primary citation | Chen, K.E.,Tillu, V.A.,Chandra, M.,Collins, B.M. Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26:1612-, 2018 Cited by PubMed: 30293811DOI: 10.1016/j.str.2018.08.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.427 Å) |
Structure validation
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