6BRW
JAK2 JH2 in complex with XMU-MP-1
Summary for 6BRW
Entry DOI | 10.2210/pdb6brw/pdb |
Descriptor | Tyrosine-protein kinase JAK2, 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide, GLYCEROL, ... (5 entities in total) |
Functional Keywords | pseudokinase domain, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 33688.58 |
Authors | Puleo, D.E.,Schlessinger, J. (deposition date: 2017-12-01, release date: 2018-08-15, Last modification date: 2023-10-04) |
Primary citation | Puleo, D.E.,Schlessinger, J. JAK2 JH2 Binders To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.031 Å) |
Structure validation
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