6BNK

Crystal structure of TCR-MHC-like molecule

6BNK の概要

• エントリーDOI: 10.2210/pdb6bnk/pdb
• 分子名称: Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, NKT Valpha14 (MOUSE) - 2C12 TCR - Hybrid mouse variable and human constant domains, ... (8 entities in total)
• 機能のキーワード: lipids cancer, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 195881.33

構造登録者

Le Nours, J.,Rossjohn, J. (登録日: 2017-11-16, 公開日: 2018-04-04, 最終更新日: 2023-10-04)

• 主引用文献: Chennamadhavuni, D.,Saavedra-Avila, N.A.,Carreno, L.J.,Guberman-Pfeffer, M.J.,Arora, P.,Yongqing, T.,Koay, H.F.,Godfrey, D.I.,Keshipeddy, S.,Richardson, S.K.,Sundararaj, S.,Lo, J.H.,Wen, X.,Gascon, J.A.,Yuan, W.,Rossjohn, J.,Le Nours, J.,Porcelli, S.A.,Howell, A.R.; Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.; Cell Chem Biol, 25:571-, 2018; PubMed: 29576533; DOI: 10.1016/j.chembiol.2018.02.009

実験手法

X-RAY DIFFRACTION (3.2 Å)