6BKB

Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3A

Summary for 6BKB

Entry DOI	10.2210/pdb6bkb/pdb
Descriptor	Fab AR3A heavy chain, Polyprotein, Fab AR3A light chain, ... (6 entities in total)
Functional Keywords	hcv, broadly neutralizing antibodies, bnabs, e2 core, ighv1-69, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	69673.65
Authors	Tzarum, N.,Wilson, I.A.,Law, M. (deposition date: 2017-11-08, release date: 2018-12-26, Last modification date: 2023-10-04)
Primary citation	Tzarum, N.,Giang, E.,Kong, L.,He, L.,Prentoe, J.,Augestad, E.,Hua, Y.,Castillo, S.,Lauer, G.M.,Bukh, J.,Zhu, J.,Wilson, I.A.,Law, M. Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies. Sci Adv, 5:eaav1882-eaav1882, 2019 Cited by PubMed: 30613781 DOI: 10.1126/sciadv.aav1882 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.799 Å)

Structure validation