6BI8

X-ray structure of MERS coronavirus papain-like protease in complex with human ISG15

6BI8 の概要

• エントリーDOI: 10.2210/pdb6bi8/pdb
• 分子名称: ORF1a, Ubiquitin-like protein ISG15, TRIETHYLENE GLYCOL, ... (9 entities in total)
• 機能のキーワード: complex, signaling protein, deisgylase, hydrolase, hydrolase-substrate complex, hydrolase/substrate
• 由来する生物種: Human betacoronavirus 2c EMC/2012; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 93570.69

構造登録者

Clasman, J.C.,Mesecar, A.D. (登録日: 2017-11-01, 公開日: 2018-11-07, 最終更新日: 2023-10-04)

• 主引用文献: Clasman, J.R.,Everett, R.K.,Srinivasan, K.,Mesecar, A.D.; Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease.; Antiviral Res., 174:104661-104661, 2020; PubMed: 31765674; DOI: 10.1016/j.antiviral.2019.104661

実験手法

X-RAY DIFFRACTION (2.291 Å)