6BFV

Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 5-fluoro-1,2-dihydropyrimidin-2-one

Summary for 6BFV

Related5CXQ
DescriptorPurine nucleoside phosphorylase, DIMETHYL SULFOXIDE, 5-fluoropyrimidin-2-ol, ... (4 entities in total)
Functional Keywordspurine nucleoside phosphorylase, transferase
Biological sourceSchistosoma mansoni (Blood fluke)
Total number of polymer chains1
Total molecular weight31940.22
Authors
Primary citation
Faheem, M.,Neto, J.B.,Collins, P.,Pearce, N.M.,Valadares, N.F.,Bird, L.,Pereira, H.M.,Delft, F.V.,Barbosa, J.A.R.G.
Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 5-fluoropyrimidin-1-ium-2-olate
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.921 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24620 1.3%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6bfv
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Molmil generated image of 6bfv
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Molmil generated image of 6bfv
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 6bfv
no rotation
Molmil generated image of 6bfv
rotated about x axis by 90°
Molmil generated image of 6bfv
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6bfv.pdb1.gz [408.98 KB])
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