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6BFV

Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 5-fluoro-1,2-dihydropyrimidin-2-one

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Purine nucleoside phosphorylasepolymer28731435.51UniProt (A0A0U3AGT1)
Pfam (PF01048)
Schistosoma mansoni (Blood fluke)Inosine-guanosine phosphorylase
2B, C, D, E, F
(A)
DIMETHYL SULFOXIDEnon-polymer78.15Chemie (DMS)
3G
(A)
5-fluoropyrimidin-2-olnon-polymer114.11Chemie (DJP)
4H
(A)
waterwater18.0104Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31435.5
Non-Polymers*Number of molecules6
Total formula weight504.7
All*Total formula weight31940.2
*Water molecules are not included.

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PDB entries from 2024-11-20

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