6BDO

Structure of bacterial type II NADH dehydrogenase from Caldalkalibacillus thermarum complexed with a quinone inhibitor HQNO at 2.8A resolution

6BDO の概要

• エントリーDOI: 10.2210/pdb6bdo/pdb
• 関連するPDBエントリー: 4NWZ 5WED
• 分子名称: FAD-dependent pyridine nucleotide-disulfide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, ... (4 entities in total)
• 機能のキーワード: rossmann fold, nadh dehydrogenase, oxidoreductase, flavo protein, membrane protein, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Caldalkalibacillus thermarum TA2.A1
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 181948.84

構造登録者

Cook, G.M.,Aragao, D.,Nakatani, Y. (登録日: 2017-10-23, 公開日: 2018-05-16, 最終更新日: 2023-10-25)

• 主引用文献: Petri, J.,Shimaki, Y.,Jiao, W.,Bridges, H.R.,Russell, E.R.,Parker, E.J.,Aragao, D.,Cook, G.M.,Nakatani, Y.; Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors.; Biochim. Biophys. Acta, 1859:482-490, 2018; PubMed: 29621505; DOI: 10.1016/j.bbabio.2018.03.014

実験手法

X-RAY DIFFRACTION (2.8 Å)