6BAI
Multiconformer model of apo K197C PTP1B at 100 K
Summary for 6BAI
Entry DOI | 10.2210/pdb6bai/pdb |
Related | 6B8E 6B8T 6B8X 6B8Z 6B90 6B95 |
Descriptor | Tyrosine-protein phosphatase non-receptor type 1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total) |
Functional Keywords | protein tyrosine phosphatase, ptp, protein tyrosine phosphatase 1b, ptp1b, enzyme, allostery, multitemperature, multiconformer, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 37441.67 |
Authors | Keedy, D.A.,Hill, Z.B.,Biel, J.T.,Kang, E.,Rettenmaier, T.J.,Brandao-Neto, J.,von Delft, F.,Wells, J.A.,Fraser, J.S. (deposition date: 2017-10-12, release date: 2018-06-20, Last modification date: 2022-03-23) |
Primary citation | Keedy, D.A.,Hill, Z.B.,Biel, J.T.,Kang, E.,Rettenmaier, T.J.,Brandao-Neto, J.,Pearce, N.M.,von Delft, F.,Wells, J.A.,Fraser, J.S. An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife, 7:-, 2018 Cited by PubMed: 29877794DOI: 10.7554/eLife.36307 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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