6B8B

E. coli LptB in complex with ADP and a novobiocin derivative

6B8B の概要

• エントリーDOI: 10.2210/pdb6b8b/pdb
• 関連するPDBエントリー: 6B89
• 分子名称: Lipopolysaccharide export system ATP-binding protein LptB, MAGNESIUM ION, (3s,5s,7s)-N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-ben zopyran-3-yl}tricyclo[3.3.1.1~3,7~]decane-1-carboxamide, ... (5 entities in total)
• 機能のキーワード: lptb, abc transporter, lps transport, lipid transport, lipid transport-activator complex, lipid transport/activator
• 由来する生物種: Escherichia coli (strain K12)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28978.90

構造登録者

Mandler, M.D.,Owens, T.W.,Lazarus, M.B.,May, J.M.,Kahne, D.K. (登録日: 2017-10-06, 公開日: 2017-12-06, 最終更新日: 2023-10-04)

• 主引用文献: May, J.M.,Owens, T.W.,Mandler, M.D.,Simpson, B.W.,Lazarus, M.B.,Sherman, D.J.,Davis, R.M.,Okuda, S.,Massefski, W.,Ruiz, N.,Kahne, D.; The Antibiotic Novobiocin Binds and Activates the ATPase That Powers Lipopolysaccharide Transport.; J. Am. Chem. Soc., 139:17221-17224, 2017; PubMed: 29135241; DOI: 10.1021/jacs.7b07736

実験手法

X-RAY DIFFRACTION (1.95 Å)