6B5K

Mycobacterium tuberculosis RmlA in complex with Mg/dTTP

Summary for 6B5K

Entry DOI	10.2210/pdb6b5k/pdb
Descriptor	Glucose-1-phosphate thymidylyltransferase, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	nucleotidyltransferase, transferase, substrate, sugar-modifying
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	2
Total formula weight	67112.08
Authors	Brown, H.A.,Holden, H.A. (deposition date: 2017-09-29, release date: 2018-02-21, Last modification date: 2023-10-04)
Primary citation	Brown, H.A.,Thoden, J.B.,Tipton, P.A.,Holden, H.M. The structure of glucose-1-phosphate thymidylyltransferase from Mycobacterium tuberculosis reveals the location of an essential magnesium ion in the RmlA-type enzymes. Protein Sci., 27:441-450, 2018 Cited by PubMed: 29076563 DOI: 10.1002/pro.3333 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation