6B5K
Mycobacterium tuberculosis RmlA in complex with Mg/dTTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006006 | biological_process | glucose metabolic process |
| A | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| A | 0019318 | biological_process | hexose metabolic process |
| A | 0046075 | biological_process | dTTP metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000271 | biological_process | polysaccharide biosynthetic process |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006006 | biological_process | glucose metabolic process |
| B | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| B | 0019318 | biological_process | hexose metabolic process |
| B | 0046075 | biological_process | dTTP metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | binding site for residue TTP A 301 |
| Chain | Residue |
| A | LEU6 |
| A | GLN24 |
| A | GLN80 |
| A | PRO83 |
| A | ASP84 |
| A | GLY85 |
| A | LEU86 |
| A | GLY107 |
| A | ASP108 |
| A | GLU193 |
| A | MG302 |
| A | ALA7 |
| A | MG303 |
| A | HOH425 |
| A | HOH434 |
| A | HOH463 |
| A | HOH471 |
| A | HOH474 |
| A | HOH483 |
| A | HOH484 |
| A | HOH486 |
| A | HOH513 |
| A | GLY8 |
| A | HOH528 |
| A | HOH536 |
| A | GLY9 |
| A | SER10 |
| A | GLY11 |
| A | THR12 |
| A | ARG13 |
| A | LYS23 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 302 |
| Chain | Residue |
| A | ASP108 |
| A | ASP222 |
| A | TTP301 |
| A | HOH425 |
| A | HOH483 |
| A | HOH528 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 303 |
| Chain | Residue |
| A | TTP301 |
| A | HOH463 |
| A | HOH474 |
| A | HOH536 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue TYD A 304 |
| Chain | Residue |
| A | MET43 |
| A | TYR112 |
| A | GLY113 |
| A | PRO114 |
| A | GLY115 |
| A | GLY117 |
| A | THR118 |
| A | SER119 |
| A | VAL247 |
| A | SER248 |
| A | GLU252 |
| A | HOH430 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ARG122 |
| A | SER125 |
| A | HOH450 |
| A | HOH466 |
| A | HOH529 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 301 |
| Chain | Residue |
| B | TTP303 |
| B | HOH435 |
| B | HOH462 |
| B | HOH481 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 302 |
| Chain | Residue |
| B | ASP108 |
| B | ASP222 |
| B | TTP303 |
| B | HOH409 |
| B | HOH426 |
| B | HOH478 |
| site_id | AC8 |
| Number of Residues | 29 |
| Details | binding site for residue TTP B 303 |
| Chain | Residue |
| B | LEU6 |
| B | GLY8 |
| B | GLY9 |
| B | SER10 |
| B | GLY11 |
| B | THR12 |
| B | ARG13 |
| B | LYS23 |
| B | GLN24 |
| B | GLN80 |
| B | PRO83 |
| B | ASP84 |
| B | GLY85 |
| B | LEU86 |
| B | GLY107 |
| B | ASP108 |
| B | GLU193 |
| B | MG301 |
| B | MG302 |
| B | HOH409 |
| B | HOH417 |
| B | HOH426 |
| B | HOH435 |
| B | HOH436 |
| B | HOH449 |
| B | HOH462 |
| B | HOH476 |
| B | HOH478 |
| B | HOH481 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | binding site for residue TYD B 304 |
| Chain | Residue |
| B | GLY113 |
| B | GLY115 |
| B | GLY117 |
| B | THR118 |
| B | SER119 |
| B | VAL247 |
| B | SER248 |
| B | GLU252 |
| B | ARG256 |
| B | HOH464 |
| B | HOH475 |
| B | MET43 |
| B | TYR112 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29076563","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6B5K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29076563","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6B5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6B5K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29076563","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6B5E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphothreonine; by PknB","evidences":[{"source":"PubMed","id":"33868202","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
