6B5E

Mycobacterium tuberculosis RmlA in complex with dTDP-glucose

6B5E の概要

• エントリーDOI: 10.2210/pdb6b5e/pdb
• 分子名称: Glucose-1-phosphate thymidylyltransferase, 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE, MAGNESIUM ION, ... (8 entities in total)
• 機能のキーワード: nucleotidyltransferase, transferase, product, sugar-modifying
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 269154.98

構造登録者

Brown, H.A.,Holden, H.M. (登録日: 2017-09-29, 公開日: 2018-02-21, 最終更新日: 2023-10-04)

• 主引用文献: Brown, H.A.,Thoden, J.B.,Tipton, P.A.,Holden, H.M.; The structure of glucose-1-phosphate thymidylyltransferase from Mycobacterium tuberculosis reveals the location of an essential magnesium ion in the RmlA-type enzymes.; Protein Sci., 27:441-450, 2018; PubMed: 29076563; DOI: 10.1002/pro.3333

実験手法

X-RAY DIFFRACTION (1.85 Å)