6AXG
Structure of RasGRP4 in complex with HRas
Summary for 6AXG
Entry DOI | 10.2210/pdb6axg/pdb |
Descriptor | RAS guanyl-releasing protein 4, GTPase HRas (2 entities in total) |
Functional Keywords | signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: Q8TDF6 Cell membrane. Isoform 2: Nucleus: P01112 |
Total number of polymer chains | 12 |
Total formula weight | 395195.29 |
Authors | Kondo, Y.,Iwig, J.S.,Kuriyan, J. (deposition date: 2017-09-06, release date: 2017-10-11, Last modification date: 2023-10-04) |
Primary citation | Vercoulen, Y.,Kondo, Y.,Iwig, J.S.,Janssen, A.,White, K.A.,Amini, M.,Barber, D.L.,Kuriyan, J.,Roose, J.P. A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1. Elife, 6:-, 2017 Cited by PubMed: 28952923DOI: 10.7554/eLife.29002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.302 Å) |
Structure validation
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