6AXF
Structure of RasGRP2 in complex with Rap1B
Summary for 6AXF
Entry DOI | 10.2210/pdb6axf/pdb |
Descriptor | RAS guanyl-releasing protein 2, Ras-related protein Rap-1b (2 entities in total) |
Functional Keywords | signaling protein, protein binding |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm, cytosol: Q7LDG7 Cell membrane: P61224 |
Total number of polymer chains | 16 |
Total formula weight | 520238.63 |
Authors | |
Primary citation | Vercoulen, Y.,Kondo, Y.,Iwig, J.S.,Janssen, A.,White, K.A.,Amini, M.,Barber, D.L.,Kuriyan, J.,Roose, J.P. A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1. Elife, 6:-, 2017 Cited by PubMed: 28952923DOI: 10.7554/eLife.29002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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