6AXD
Structures of REV1 UBM2 domain complex with ubiquitin and with the first small-molecule that inhibits the REV1 UBM2-ubiquitin interaction
Summary for 6AXD
Entry DOI | 10.2210/pdb6axd/pdb |
NMR Information | BMRB: 30340 |
Descriptor | DNA repair protein REV1 (1 entity in total) |
Functional Keywords | ubiquitin-binding motif, structural protein, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 7813.63 |
Authors | Fujii, N.,Vanarotti, M. (deposition date: 2017-09-06, release date: 2018-06-27, Last modification date: 2024-05-01) |
Primary citation | Vanarotti, M.,Grace, C.R.,Miller, D.J.,Actis, M.L.,Inoue, A.,Evison, B.J.,Vaithiyalingam, S.,Singh, A.P.,McDonald, E.T.,Fujii, N. Structures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2-Ubiquitin Interaction. J. Mol. Biol., 430:2857-2872, 2018 Cited by PubMed: 29864443DOI: 10.1016/j.jmb.2018.05.042 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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