6AXD

Structures of REV1 UBM2 domain complex with ubiquitin and with the first small-molecule that inhibits the REV1 UBM2-ubiquitin interaction

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA repair protein REV1	polymer	72	7813.6	1	UniProt (Q9UBZ9) Pfam (PF14377)	Homo sapiens (Human)	Alpha integrin-binding protein 80,AIBP80,Rev1-like terminal deoxycytidyl transferase

Sequence modifications

A: 30 - 72 (UniProt: Q9UBZ9)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Leu 13	-	expression tag
Asn 14	-	expression tag
Gly 15	-	expression tag
Ser 16	-	expression tag
Ser 17	-	expression tag
Leu 18	-	expression tag
Val 19	-	expression tag
Pro 20	-	expression tag
Arg 21	-	expression tag
Gly 22	-	expression tag
Ser 23	-	expression tag
Ile 24	-	expression tag
Lys 25	-	expression tag
Ser 26	-	expression tag
Ser 27	-	expression tag
Gly 28	-	expression tag
Leu 29	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	7813.6
All*	Total formula weight	7813.6

*Water molecules are not included.