6AW8
2.25A resolution domain swapped dimer structure of SAH bound catechol O-methyltransferase (COMT) from Nannospalax galili
Summary for 6AW8
Entry DOI | 10.2210/pdb6aw8/pdb |
Descriptor | Catechol O-methyltransferase, CALCIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total) |
Functional Keywords | spalax, comt, s-adenosylmethionine binding, transferase |
Biological source | Nannospalax galili |
Total number of polymer chains | 3 |
Total formula weight | 78425.59 |
Authors | Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Deng, Y.,Hanzlik, R.P.,Shams, I.,Moskovitz, J. (deposition date: 2017-09-05, release date: 2018-09-12, Last modification date: 2023-10-04) |
Primary citation | Deng, Y.,Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Hanzlik, R.P.,Shams, I.,Moskovitz, J. Crystal structure of the catechol-o-methyl transferase (COMT) enzyme of the subterranean mole rat (Spalax) and the effect of L136M substitution To be published, |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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