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6ATT

39S Fab bound to HER2 ecd

Summary for 6ATT
Entry DOI10.2210/pdb6att/pdb
DescriptorReceptor tyrosine-protein kinase erbB-2, Antibody 39S Fab heavy chain, Antibody 39S Fab light chain, ... (5 entities in total)
Functional Keywordsantibody, fragment antigen binding, her2, receptor, immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight118521.35
Authors
Oganesyan, V.Y.,Dall'Acqua, W.F. (deposition date: 2017-08-29, release date: 2018-04-25, Last modification date: 2023-10-04)
Primary citationOganesyan, V.,Peng, L.,Bee, J.S.,Li, J.,Perry, S.R.,Comer, F.,Xu, L.,Cook, K.,Senthil, K.,Clarke, L.,Rosenthal, K.,Gao, C.,Damschroder, M.,Wu, H.,Dall'Acqua, W.
Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody.
J. Biol. Chem., 293:8439-8448, 2018
Cited by
PubMed: 29669810
DOI: 10.1074/jbc.M117.818013
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.77 Å)
Structure validation

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