6AQJ
Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activity.
Summary for 6AQJ
| Entry DOI | 10.2210/pdb6aqj/pdb |
| Related | 5W3K |
| Descriptor | Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, oxo(propan-2-ylamino)acetic acid, ... (8 entities in total) |
| Functional Keywords | reductoisomerase, complex, inhibitor, ipoha, isomerase |
| Biological source | Staphylococcus aureus |
| Total number of polymer chains | 2 |
| Total formula weight | 78147.99 |
| Authors | Patel, K.M.,Teran, D.,Zheng, S.,Gracia, M.,Lv, Y.,Schembri, M.A.,McGeary, R.P.,Schenk, G.,Guddat, L.W. (deposition date: 2017-08-20, release date: 2017-10-18, Last modification date: 2023-10-04) |
| Primary citation | Patel, K.M.,Teran, D.,Zheng, S.,Kandale, A.,Garcia, M.,Lv, Y.,Schembri, M.A.,McGeary, R.P.,Schenk, G.,Guddat, L.W. Crystal Structures of Staphylococcus aureus Ketol-Acid Reductoisomerase in Complex with Two Transition State Analogues that Have Biocidal Activity. Chemistry, 23:18289-18295, 2017 Cited by PubMed: 28975665DOI: 10.1002/chem.201704481 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.373 Å) |
Structure validation
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