6APL

Crystal Structure of human ST6GALNAC2 in complex with CMP

Summary for 6APL

Entry DOI	10.2210/pdb6apl/pdb
Descriptor	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, CYTIDINE-5'-MONOPHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	glycosyltransferase, transferase, structural genomics, psi-biology, northeast structural genomics consortium, nesg
Biological source	Homo sapiens (Human)
Cellular location	Golgi apparatus membrane ; Single-pass type II membrane protein : Q9UJ37
Total number of polymer chains	6
Total formula weight	257780.12
Authors	Forouhar, F.,Moremen, K.W.,Northeast Structural Genomics Consortium (NESG),Tong, L. (deposition date: 2017-08-17, release date: 2017-12-20, Last modification date: 2024-04-03)
Primary citation	Moremen, K.W.,Ramiah, A.,Stuart, M.,Steel, J.,Meng, L.,Forouhar, F.,Moniz, H.A.,Gahlay, G.,Gao, Z.,Chapla, D.,Wang, S.,Yang, J.Y.,Prabhakar, P.K.,Johnson, R.,Rosa, M.D.,Geisler, C.,Nairn, A.V.,Seetharaman, J.,Wu, S.C.,Tong, L.,Gilbert, H.J.,LaBaer, J.,Jarvis, D.L. Expression system for structural and functional studies of human glycosylation enzymes. Nat. Chem. Biol., 14:156-162, 2018 Cited by PubMed: 29251719 DOI: 10.1038/nchembio.2539 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation