6AGM

Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli

Summary for 6AGM

• Entry DOI: 10.2210/pdb6agm/pdb
• Descriptor: Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive, TYROSINE (3 entities in total)
• Functional Keywords: 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase (dahp synthase), escherichia coli, aromatic amino acid biosynthesis, feedback inhibition, allosteric regulation., biosynthetic protein
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 4
• Total formula weight: 155824.04

Authors

Cui, D.,Qi, J.,Wen, T. (deposition date: 2018-08-13, release date: 2019-04-17, Last modification date: 2023-11-22)

• Primary citation: Cui, D.,Deng, A.,Bai, H.,Yang, Z.,Liang, Y.,Liu, Z.,Qiu, Q.,Wang, L.,Liu, S.,Zhang, Y.,Shi, Y.,Qi, J.,Wen, T.; Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli.; J.Struct.Biol., 206:322-334, 2019; PubMed: 30946901; DOI: 10.1016/j.jsb.2019.04.001

Experimental method

X-RAY DIFFRACTION (2 Å)