6AGM

Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
A	0005737	cellular_component	cytoplasm
A	0008652	biological_process	amino acid biosynthetic process
A	0009058	biological_process	biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0016740	molecular_function	transferase activity
A	0042802	molecular_function	identical protein binding
B	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
B	0005737	cellular_component	cytoplasm
B	0008652	biological_process	amino acid biosynthetic process
B	0009058	biological_process	biosynthetic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0009423	biological_process	chorismate biosynthetic process
B	0016740	molecular_function	transferase activity
B	0042802	molecular_function	identical protein binding
C	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
C	0005737	cellular_component	cytoplasm
C	0008652	biological_process	amino acid biosynthetic process
C	0009058	biological_process	biosynthetic process
C	0009073	biological_process	aromatic amino acid family biosynthetic process
C	0009423	biological_process	chorismate biosynthetic process
C	0016740	molecular_function	transferase activity
C	0042802	molecular_function	identical protein binding
D	0003849	molecular_function	3-deoxy-7-phosphoheptulonate synthase activity
D	0005737	cellular_component	cytoplasm
D	0008652	biological_process	amino acid biosynthetic process
D	0009058	biological_process	biosynthetic process
D	0009073	biological_process	aromatic amino acid family biosynthetic process
D	0009423	biological_process	chorismate biosynthetic process
D	0016740	molecular_function	transferase activity
D	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue TYR A 601

Chain	Residue
A	PRO148
A	LEU222
A	HOH777
A	PRO151
A	GLN152
A	GLY179
A	LEU180
A	SER181
A	PHE210
A	GLY212
A	ILE213

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site_id	AC2
Number of Residues	9
Details	binding site for residue TYR B 601

Chain	Residue
B	PRO148
B	PRO151
B	GLN152
B	GLY179
B	LEU180
B	SER181
B	GLY212
B	ILE213
B	LEU222

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site_id	AC3
Number of Residues	10
Details	binding site for residue TYR C 601

Chain	Residue
C	PRO148
C	PRO151
C	GLN152
C	GLY179
C	LEU180
C	SER181
C	GLY212
C	ILE213
C	LEU222
C	HOH750

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site_id	AC4
Number of Residues	10
Details	binding site for residue TYR D 601

Chain	Residue
D	PRO148
D	PRO151
D	GLN152
D	GLY179
D	LEU180
D	SER181
D	GLY212
D	ILE213
D	LEU222
D	HOH746

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