6A88
Crystal Structure of T. gondii prolyl tRNA synthetase with Febrifugine and ATP Analog
Summary for 6A88
| Entry DOI | 10.2210/pdb6a88/pdb |
| Descriptor | Prolyl-tRNA synthetase (ProRS), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | prs, drug, parasite, atp, translation |
| Biological source | Toxoplasma gondii ME49 |
| Total number of polymer chains | 4 |
| Total formula weight | 235076.40 |
| Authors | Kumari, S.,Mishra, S.,Yogavel, M.,Sharma, A. (deposition date: 2018-07-06, release date: 2019-10-23, Last modification date: 2023-11-22) |
| Primary citation | Mishra, S.,Malhotra, N.,Kumari, S.,Sato, M.,Kikuchi, H.,Yogavel, M.,Sharma, A. Conformational heterogeneity in apo and drug-bound structures of Toxoplasma gondii prolyl-tRNA synthetase. Acta Crystallogr.,Sect.F, 75:714-724, 2019 Cited by PubMed: 31702585DOI: 10.1107/S2053230X19014808 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.596 Å) |
Structure validation
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