6YYY
Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 4,4-dimethyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser)
Summary for 6YYY
Entry DOI | 10.2210/pdb6yyy/pdb |
Descriptor | Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, MANGANESE (II) ION, ... (5 entities in total) |
Functional Keywords | aspartyl/asparaginyl beta-hydroxylase, dioxygenase, oxidoreductase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 53824.81 |
Authors | Nakashima, Y.,Brewitz, L.,Schofield, C.J. (deposition date: 2020-05-06, release date: 2021-03-17, Last modification date: 2024-02-07) |
Primary citation | Brewitz, L.,Nakashima, Y.,Schofield, C.J. Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase. Chem Sci, 12:1327-1342, 2020 Cited by PubMed: 34163896DOI: 10.1039/d0sc04301j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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