6YYY
Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 4,4-dimethyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Aspartyl/asparaginyl beta-hydroxylase | polymer | 429 | 49405.3 | 1 | UniProt (Q12797) Pfam (PF13432) Pfam (PF05118) In PDB | Homo sapiens (Human) | Aspartate beta-hydroxylase,ASP beta-hydroxylase,Peptide-aspartate beta-dioxygenase |
| 2 | B | Coagulation factor X | polymer | 39 | 4190.4 | 1 | UniProt (P00742) Pfam (PF00008) In PDB | Homo sapiens (Human) | Stuart factor,Stuart-Prower factor |
| 3 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 4 | A | 2,2-dimethyl-4-oxidanylidene-pentanedioic acid | non-polymer | 174.2 | 1 | Chemie (Q1W) | |||
| 5 | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
B: 86 - 124 (UniProt: P00742)
| PDB | External Database | Details |
|---|---|---|
| Ser 90 | Cys 90 | engineered mutation |
| Ser 95 | Cys 95 | engineered mutation |
| Ser 112 | Cys 112 | engineered mutation |
| Ser 121 | Cys 121 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53595.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 229.1 | |
| All* | Total formula weight | 53824.8 |
