6YKH
Metala-Carborane di-ethyl-sulfonamide (cis isomer) in complex with CA IX mimic
Summary for 6YKH
Entry DOI | 10.2210/pdb6ykh/pdb |
Related | 6YJ3 6YKC |
Descriptor | Carbonic anhydrase 2, ZINC ION, Metala-Carborane di-ethyl-sulfonamide, ... (4 entities in total) |
Functional Keywords | carbonic anhydrase, ca inhibitor, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 29787.17 |
Authors | Kugler, M.,Brynda, J.,Pospisilova, K.,Rezacova, P. (deposition date: 2020-04-06, release date: 2020-09-09, Last modification date: 2024-01-24) |
Primary citation | Gruner, B.,Kugler, M.,El Anwar, S.,Holub, J.,Nekvinda, J.,Bavol, D.,Ruzickova, Z.,Pospisilova, K.,Fabry, M.,Kral, V.,Brynda, J.,Rezacova, P. Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX. Chempluschem, 86:352-363, 2021 Cited by PubMed: 32955786DOI: 10.1002/cplu.202000574 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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